NCBL

UNIVERSITY OF ALBERTA

Mozhgan Sabz

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About me

I graduated from Shiraz University, Shiraz, Iran in2016 with a M. Sc. In Mechanical engineering under the supervision of Prof. Reza Kamali. Currently, I am pursuing my Ph. D. in the mechanical engineering department of University of Alberta.

Supervisors:

  • Dr. Andrew Martin

  • Dr. Hossein Rouhani

Research interests:

  • Biomechanics, Medical devices, Drug delivery

  • Multiphase flow

  • Fluid mechanics, Fluid dynamics

Projects:

Current Project

It is common to use additional oxygen therapy in acute care hospitals and in long-term care facilities. It is problematic as well as dangerous to deliver oxygen at an improper amount. There are clinical situations in which oxygen is needed, but nasal cannula has different properties, causing it to be difficult to determine the percentage of inspired oxygen. This study has three different parts:

1)This study uses our research group's work on in vitro benchtop testing methods for medical gas delivery devices that provide oxygen to newborns and infants. Through an in vitro method, we evaluate low-flow oxygen therapy in neonates and infants. A novel correlation is established to predict the fraction of oxygen in trachea (FiO2), accounting for variability between subjects and between breaths.

2) a realistic upper airway replica of an adult is used to simulate various breathing patterns. We combine FiO2 values measured in an adult replica with previously determined values measured in neonates to establish a single relationship for FiO2, based on nasal cannula oxygen flow rate and inhaled air (dependent on tidal volume (Vt) and inhalation time(ti)), that applies to all age groups and nasal cannula flow rates within the range of low flow oxygen delivery.

3)A controlling system will be developed with the goal of improving automatic oxygen delivery. FiO2 is determined by applying the derived equations from the previous parts of the study and calculated FiO2 values allow prediction of the change of oxygen saturation in blood(SpO2) within the next few minutes.

After graduation researches    Project of tunnel ventilation

My groupmates and I did a project for ventilation of Taloon Tunnels, which connect Tehran to North in Iran, in order to find the best combination of axial fans and jet fans with and without considering fire and traffic. In fire condition, we tried to provide a ventilation system to make balance at the both sides of fire so as to prevent smoke propagation.

In another study, at the first step, semi-transverse ventilation system was evaluated by considering the effect of pressurizing the service tunnel. Secondly, the possibility of ingress of air from the main tunnel in emergency condition into service tunnel or another main tunnel was investigated. 

Sep. 2014 - Sep.2016        Graduate thesis: Numerical Simulation of Magnetic Drug Targeting to a Tumor in the Human Lung (19.5 out of 20)

  • Using SolidWorks to model bifurcations and COMSOL to analyze fluid flow

  • Applying an external magnetic field by a carrying-current coil

  • Assuming laminar fluid flow and particles are coupled with the fluid by one-way method

  • Reporting the influences of various parameters such as particle diameter, magnetic source position, current intensity, inlet mass flow rate and tumor size on the deposition efficiency (DE) on the tumor surface

  • Finding appropriate regions for particle releasing in the absence and presence of magnetic field

  • Comparing different methods for drug delivery and Finding the best method for drug delivery to intended tumor

Sep. 2011 - Sep. 2012       Undergraduate thesis: 3-D Simulation of a MAV in the Fluid Flow (19.5 out of 20)

  • discussing the effect of wing shape on air flow around the wing

Sep. 2009 - Feb. 2012       Undergraduate researches

  • Water Transmission System projects

         Project of water transmission network for the Aspas plain (EPANET software)

Project of water transmission network for the Golestan town (Water Hammer)  

  • Various Computational Fluid Dynamic (CFD) projects

  • Heat conduction projects

  • Power plants projects

Publications:

  • Ready for submit paper: Variability in Low-flow Oxygen Delivery by Nasal Cannula Evaluated in Neonatal and Infant Airway Replicas" /M. Sabz, S. Tavernini, K. Pillay, C. Christianson, M. Noga, W. H. Finlay, H. Rouhani, A.R. Martin

  • Published paper: M. Sabz, R. Kamali, S. Ahmadizade "Numerical Simulation of Magnetic Drug Targeting to a Tumor in the Simplified Model of the Human Lung". Computer Methods and Programs in Biomedicine 172 (2019) 11-24.

  • Published paper: M. Sabz, R. Kamali, S. Ahmadizade " Controlled Release of Magnetic Particles for Drug Delivery in the Human Lung ". IEEE Transactions on Magnetics

  • Ready for submit paper: Omid Abouali, Alireza Dastan, Mozhgan Sabz " The challenges of balancing the airflow in both sides of a zone with open dampers in semi-transverse ventilation of a 4.9 km tunnel- A CFD study". Shiraz University, project of ventilation of Taloon Tunnel, which connect Tehran to North.

  • Ready for submit paper: Omid Abouali, Alireza Dastan, Mozhgan Sabz " evaluating ventilation of a long tunnel by considering cross-passages and cross-overs". Shiraz University, project of ventilation of Taloon Tunnel, which connect Tehran to North.

Posters:

  • Variability in Low-flow Oxygen Delivery by Nasal Cannula Evaluated in Neonatal and Infant Airway Replicas", ATS conference, Sanfrancisco, California, US, May 15-18-2022

Honors:

  • Ranked in top 1%, Nationwide University Entrance Exam for M.Sc. program with more than 15,000 participants

  • Accepted in national first level of Physics Olympiad

  • Ranked 1st, in all high school levels, Yasuj, Iran.

  • Ranked 3st, in GPA, among 28 Students in M.Sc. program/Mechanical Engineering, Shiraz University, Shiraz, Iran